A comparative field trial of five measles vaccines produced in human diploid cell, MRC-5

Authors

A. SHAFYI

H. MIRCHAMSY

J. RAZAVI

M. AMIN-SALEHI

M. KAMALI

P. AHOURAI

P. NAZARI

S. BAHRAMI

S. FATEMI

Abstract:

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a comparative field trial of five measles vaccines produced in hum an diploid cell, mrc-5

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A comparative field trial of five measles vaccines produced in human diploid cell, MRC-5.

Five batches of experimental measles vaccines were prepared with Biken-CAM, Schwarz, Sugiyama, Leningrade-16 and AIK-C strains in MRC-5 HDC. The rct 40, T50 or neurovirulence for baby hamsters of these viruses adapted to HOC were not significantly changed but the neurovirulence of the Sugiyama virus for day-old hamsters was increased after passages in HOC. Whith the exception of the AIK-C strai...

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